Vísindarannsóknir
Rannsóknir og nýsköpun hefur ávallt verið ein af grunnstoðum Blóðbankans og í dag fer þar fram öflugt rannsóknar- og nýsköpunarstarf m.a. á sviði stofnfrumurannsókna, frumumeðferða, vefjaverkfræði og blóðbankafræði. Markmið rannsóknar- og nýsköpunarstarfs Blóðbankans er að brúa bilið á milli tilraunavísinda og læknisfræðilegra rannsókna til að skapa jarðveg fyrir nýjungar í læknisfræði á sviði stofnfruma, vefjaverkfræði og blóðbankafræða á Íslandi.
Undanfarin ár hafa verið gjöful á sviði rannsókna og nýsköpunar í Blóðbankanum. Hægt er að þakka það mikilli vinnu starfsmanna, frábæru samstarfsfólki innanlands og erlendis auk hóps af hæfileikaríkum nemendum sem gegna lykilhlutverki í rannsóknar og nýsköpunarstarfi í Blóðbankanum. Blóðbankinn lítur á rannsóknir og nýsköpun og þjálfun nema sem eina af undirstöðum blóðbankaþjónustu á Íslandi og hefur innleitt vísindastefnu til að marka spor til framtíðar.
Deild rannsókna og nýsköpunar er stýrt af Dr. Ólafi E. Sigurjónssyni prófessor við verkfræðideild Háskólans í Reykjavík og klínískum prófessor við læknadeild Háskóla Íslands. Þar að auki býr Blóðbankinn yfir reynslumiklum vísindamönnum sem hafa í gegnum árin verið öflug á sviði grunnrannsókna, Dr. Sveinn Guðmundsson, yfirlæknir, Dr. Steinunn Thorlacius verkefnastjóri, Dr. Þorbjörn Jónsson klínískur prófessor við læknadeild HÍ og sérfræðilæknir í Blóðbankanum
Brynjolfsson SF, Sigurgrimsdottir H, Einarsdottir ED, Bjornsdottir GA, Armannsdottir B, Baldvinsdottir GE, Bjarnason A, Gudlaugsson O, Gudmundsson S, Sigurdardottir ST, Love A, Kristinsson KG, Ludviksson BR. Detailed Multiplex Analysis of SARS-CoV-2 Specific Antibodies in COVID-19 Disease. Front Immunol. 2021 Jun 10;12:695230. doi: 10.3389/fimmu.2021.695230.
Clausen FB, Hellberg Å, Bein G, Bugert P, Schwartz D, Drnovsek TD, Finning K, Guz K, Haimila K, Henny C, O'Brien H, Orzinska A, Sørensen K, Thorlacius S, Wikman A, Denomme GA, Flegel WA, Gassner C, de Haas M, Hyland C, Ji Y, Lane WJ, Nogués N, Olsson ML, Peyrard T, van der Schoot CE, Weinstock C, Legler T. Recommendation for validation and quality assurance of non-invasive prenatal testing for foetal blood groups and implications for IVD risk classification according to EU regulations. Vox Sang. 2021 Jun 21. doi: 10.1111/vox.13172.
Deak D, Gorcea-Andronic N, Sas V, Teodorescu P, Constantinescu C, Iluta S, Pasca S, Hotea I, Turcas C, Moisoiu V, Zimta AA, Galdean S, Steinheber J, Rus I, Rauch S, Richlitzki C, Munteanu R, Jurj A, Petrushev B, Selicean C, Marian M, Soritau O, Andries A, Roman A, Dima D, Tanase A, Sigurjonsson O, Tomuleasa C. A narrative review of central nervous system involvement in acute leukemias. Ann Transl Med. 2021 Jan;9(1):68. doi: 10.21037/atm-20-3140.
Milewska A, Sigurjonsson OE, Leosson K. SERS Imaging of Mesenchymal Stromal Cell Differentiation. ACS Applied Bio Materials. 2021;4(6):4999-5007.doi:10.1021/acsabm.1c00286.
Sigmarsdottir TB, McGarrity S, Yurkovich JT, Rolfsson Ó, Sigurjónsson ÓE. Analyzing Metabolic States of Adipogenic and Osteogenic Differentiation in Human Mesenchymal Stem Cells via Genome Scale Metabolic Model Reconstruction. Front Cell Dev Biol. 2021;9:642681. Published 2021 Jun 4. doi:10.3389/fcell.2021.642681
Živanović V, Milewska A, Leosson K, Kneipp J. Molecular Structure and Interactions of Lipids in the Outer Membrane of Living Cells Based on Surface-Enhanced Raman Scattering and Liposome Models. Anal Chem. 2021;93(29):10106-10113. doi:10.1021/acs.analchem.1c00964
Sigmarsdottir TB, McGarrity S, de Lomana ALG, Kotronoulas A, Sigurdsson S, Yurkovich JT, Rolfsson O, Sigurjonsson OE. Metabolic and Transcriptional Changes across Osteogenic Differentiation of Mesenchymal Stromal Cells. Bioengineering (Basel). 2021 Dec 10;8(12):208. doi: 10.3390/bioengineering8120208. PMID: 34940360; PMCID: PMC8698318.
Metabolic and Transcriptional Changes across Osteogenic Differentiation of Mesenchymal Stromal Cells. Sigmarsdottir TB, McGarrity S, de Lomana ALG, Kotronoulas A, Sigurdsson S, Yurkovich JT, Rolfsson O, Sigurjonsson OE. Bioengineering (Basel). 2021 Dec 10;8(12):208. doi: 10.3390/bioengineering8120208.
Dalma Deak, Nicolae Gorcea-Andronic, Valentina Sas, Patric Teodorescu, Catalin Constantinescu, Sabina Iluta, Sergiu Pasca, Ionut Hotea, Cristina Turcas, Vlad Moisoiu, Alina-Andreea Zimta, Simona Galdean, Jakob Steinheber, Ioana Rus, Sebastian Rauch, Cedric Richlitzki, Raluca Munteanu, Ancuta Jurj, Bobe Petrushev, Cristina Selicean, Mirela Marian, Olga Soritau, Alexandra Andries, Andrei Roman, Delia Dima, Alina Tanase, Olafur Sigurjonsson and Ciprian Tomuleasacorresponding . A narrative review of central nervous system involvement in acute leukemias . Ann Transl Med. 2021 Jan; 9(1): 68. doi: 10.2137/atm-20-3140
SERS Imaging of Mesenchymal Stromal Cell Differentiation. A Milewska, OE Sigurjonsson, K Leosson. ACS CS Appl. Bio Mater. 2021, 4, 6, 4999–5007. Doi: 10.1021/acsabm.1c00286
Analyzing metabolic states of adipogenic and osteogenic differentiation in human mesenchymal stem cells via genome scale metabolic model reconstruction. TB Sigmarsdottir, S McGarrity, JT Yurkovich, Ó Rolfsson, ÓE Sigurjónsson. Front. Cell Dev. Biol., 04 June 2021. https://doi.org/10.3389/fcell.2021.642681
Marta Mikaelsdottir, Brynjar Vidarsson, Gudmundur Runarsson, Una Bjarnadottir, Pall T. Onundarson Olafur E. Sigurjonsson, Anna M. Halldorsdottir. A comparison of platelet quality between platelets from healthy donors and hereditary hemochromatosis donors over seven‐day storage. Transfusion, First published: 09 November 2020. https://doi.org/10.1111/trf.16176
Marta Mikaelsdottir, Brynjar Vidarsson, Gudmundur Runarsson, Una Bjarnadottir, Pall T. Onundarson Olafur E. Sigurjonsson, Anna M. Halldorsdottir. A comparison of platelet quality between platelets from healthy donors and hereditary hemochromatosis donors over seven‐day storage. Transfusion, First published: 09 November 2020. https://doi.org/10.1111/trf.16176
B Cells versus T Cells in the Tumor Microenvironment of Malignant Lymphomas. Are the Lymphocytes Playing the Roles of Muhammad Ali versus George Foreman in Zaire 1974? Minodora Desmirean , Sebastian Rauch, Ancuta Jurj, Sergiu Pasca, Sabina Iluta, Patric Teodorescu, Cristian Berce , Alina-Andreea Zimta, Adrian-Bogdan Tigu, Cristian Moldovan, Irene Paris, Jakob Steinheber, Cedric Richlitzki, Catalin Constantinescu, Olafur Eysteinn Sigurjonsson, Delia Dima, Bobe Petrushev and Ciprian Tomuleasa. J. Clin. Med. 2020, 9(11), 3412; https://doi.org/10.3390/jcm9113412
Overview of the Side-Effects of FDA- and/or EMA-Approved Targeted Therapies for the Treatment of Hematological Malignancies. Catalin Constantinescu, Sergiu Pasca, Alina-Andreea Zimta,Tiberiu Tat, Ioana Rus ,Patric Teodorescu,Sabina Iluta, Alina Tanase , Anca Colita , Olafur Sigurjonsson ,Hermann Einsele and Ciprian Tomuleasa. J. Clin. Med. 2020, 9(9), 2903; https://doi.org/10.3390/jcm9092903
Rhesus D alloimmunization in pregnancy from 1996 to 2015 in Iceland: a nation-wide population study prior to routine antenatal anti-D prophylaxis.Gudlaugsson B, Hjartardottir H, Svansdottir G, Gudmundsdottir G, Kjartansson S, Jonsson T, Gudmundsson S, Halldorsdottir AM. Transfusion. 2020 Jan;60(1):175-183. https://doi.org/10.1111/trf.15635
The Malignant Role of Exosomes as Nanocarriers of Rare RNA Species. Alina-Andreea Zimta , Olafur Eysteinn Sigurjonsson, Diana Gulei and Ciprian Tomuleasa. J. Mol. Sci. 2020, 21(16), 5866. https://dx.doi.org/10.3390%2Fijms21165866
Human Embryonic-Derived Mesenchymal Progenitor Cells (hES-MP Cells) are Fully Supported in Culture with Human Platelet Lysates. Jonsdottir-Buch SM, Gunnarsdottir K, Sigurjonsson OE. Bioengineering (Basel). 2020 Jul 20;7(3):E75. https://doi.org/10.3390/bioengineering7030075
Continuous renal replacement therapy in cytokine release syndrome following immunotherapy or cellular therapies? . Constantinescu C, Pasca S, Tat T, Teodorescu P, Vlad C, Iluta S, Dima D, Tomescu D, Scarlatescu E, Tanase A, Sigurjonsson OE, Colita A, Einsele H, Tomuleasa C. J Immunother Cancer. 2020 May;8(1):e000742. https://doi.org/10.1136/jitc-2020-000742
Effects of amotosalen treatment on human platelet lysate bioactivity: A proof-of-concept study. Christensen C, Jonsdottir-Buch SM, Sigurjonsson OE. PLoS One. 2020 Apr 15;15(4):e0220163. https://dx.doi.org/10.1371%2Fjournal.pone.0220163
Current Status and Future Prospects of Genome-Scale Metabolic Modeling to Optimize the Use of Mesenchymal Stem Cells in Regenerative Medicine. Sigmarsdóttir Þ, McGarrity S, Rolfsson Ó, Yurkovich JT, Sigurjónsson ÓE. Front Bioeng Biotechnol. 2020; 8: 239. https://dx.doi.org/10.3389%2Ffbioe.2020.00239
Visualizing metabolic network dynamics through time-series metabolomic data. Buchweitz LF, Yurkovich JT, Blessing C, Kohler V, Schwarzkopf F, King ZA, Yang L, Jóhannsson F, Sigurjónsson ÓE, Rolfsson Ó, Heinrich J, Dräger A. BMC Bioinformatics. 2020 Apr 3;21(1):130. https://doi.org/10.1186/s12859-020-3415-z
Metabolomics study of platelet concentrates photochemically treated with amotosalen and UVA light for pathogen inactivation. Jóhannsson F, Árnason NÁ, Landrö R, Guðmundsson S, Sigurjonsson ÓE, Rolfsson Ó.Transfusion. 2020 Feb;60(2):367-377. https://doi.org/10.1111/trf.15610
Stefaniak, M, Gudjonsdottir M and Sigurjonsson OE. Fucoidan oligosaccharides-gold from the sea. Encyclopedia of Marine Biotechnology, Chapter 46. ISBN: 978-1-119-14377-2Wiley-Blackwell. https://doi.org/10.1002/9781119143802.ch46
Johannesdottir BK, Johannesdottir U, Jonsson T, Lund SH, Mogensen B, Gudbjartsson T. High Mortality from Major Vascular Trauma in Traffic Accidents: A Population-Based Study. Scand J Surg. 2020 Dec;109(4):328-335. https://doi.org/10.1177/1457496919863944
Sarah McGarrity, Sigurður T. Karvelsson, Olafur E. Sigurjonsson, andOttar Rolfsson. ComparativeMetabolic Network FluxAnalysistoIdentifyDifferencesinCellularMetabolism. MethodsandProtocols, MethodsinMolecularBiology, vol. 2088: 223-269. Springer 2019. https://doi.org/10.1007/978-1-0716-0159-4_11
Gold nanoislandsubstrates for SERS characterization of culturedcells.Milewska A, Zivanovic V, Merk V, Arnalds UB, Sigurjónsson ÓE, Kneipp J, Leosson K.BiomedOpt Express. 2019 Nov 8;10(12):6172-6188. https://doi.org/10.1364/boe.10.006172
A standalone bioreactor system to deliver compressive load under perfusion flow to hBMSC-seeded 3D chitosan-graphene templates. Lovecchio J, Gargiulo P, Vargas Luna JL, Giordano E, Sigurjónsson ÓE. Sci Rep. 2019 Nov 14;9(1):16854. https://doi.org/10.1038/s41598-019-53319-7
Pathogen inactivation with amotosalen plus UVA illumination minimally impacts microRNA expression in platelets during storage under standard blood banking conditions.
Arnason NA, Johannson F, Landrö R, Hardarsson B, Irsch J, Gudmundsson S, Rolfsson O, Sigurjonsson OE. Transfusion. 2019 Dec;59(12):3727-3735. https://doi.org/10.1111/trf.15575
A Milewska, AS Ingason, OE Sigurjonsson, K Leosson. Herding cats: managing gold atoms on common transparent dielectrics. Optical Materials Express. 2019, 9 (1), 112-119. https://doi.org/10.1364/OME.9.000112
Stefaniak, M. M., Marteinsdottir, G., Bravo, E., Sigurjonsson, O. E., & Kristbergsson, K. (2019). Determination of bioactiveproperties of extracts from Icelandicediblebrownseaweedsugarkelp (Saccharinalatissima)Functional Foods in Health andDisease 9 (1), 1-15. https://doi.org/10.31989/ffhd.v9i1.546
Clausen FB, Barrett AN, Akkok CA, Armstrong-Fisher S, Bergstrom KD, Boggione CT, Baevre MS, Choolani M, Christiansen M, Cotorruelo C, Drnovsek TD, Finning K, Guz K, de Haas M, Haimila K, Halldorsdottir AM, Hellberg A, Henny C, Holmertz C, Al Houghton J, Hyland C, Jakobsen MA, Kvitland MA, Lambert M, Legler TJ, Liew Y-W, Muniz-Diaz E, Mortberg A, Niederhauser C, Nogues N, Nystrom S, Olsson ML, Orzinska A, Parks M, Rietkotter E, Ryan H, Sachs UJ, van der Schoot E, Silcock L, Steffensen R, Sulin K, Sorensen AS, Tarrant S, Thorlacius S, Wienzek-Lischka S, Wikman A, Wulf-Johansson H, Zupan M, Dziegiel MH. VoxSang. 2019 May;114(4):386-393. https://doi.org/10.1111/vox.12768
MG, Jonsson T, Halldorsdottir AM. CirculatingplasmamicroRNAsasbiomarkers for iron status inblooddonors. TransfusionMedicine. 2019 Apr;29 Suppl 1:52-58. https://doi.org/10.1111/tme.12554
Thorvaldsson HH, Vidarsson B, Sveinsdottir SV, Olafsson GB, Halldorsdottir AM. Redbloodcellutilizationandtransfusiontriggersinpatientsdiagnosed with chroniclymphocyticleukaemiain Iceland 2003-2016.Vox Sang. 2019 Jul;114(5):495-504. https://doi.org/10.1111/vox.12775
Anna Margret Halldorsdottir, Sveinlaug Atladottir, Margret A. Thorsteinsdottir, Niels A. Arnason, Gudmundur Runarsson, Torbjorn Jonsson, Olafur E. Sigurjonsson, Sigrun Reykdal. To wash or not to wash?: Comparison of patient outcome after infusion of cryopreserved autologous hematopoietic stem cells before and after the replacement of manual washing by bedside thawing. Acta Hematalogica 2 018;140(3):169-175. https://doi.org/10.1159/000492741
Jóhannsson F, Guðmundsson S, Paglia G, Guðmundsson S, Palsson B, Sigurjónsson ÓE, Rolfsson Ó Systems analysis of metabolism in platelet concentrates during storage in platelet additive solution. Biochem J. 2018 Jul 17;475(13):2225-2240. doi: https://doi.org/10.1042/bcj20170921
POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression. Bjorg Gudmundsdottir, Kristbjorn O. Gudmundsson, Kimberly D. Klarmann, Satyendra K. Singh, Lei Sun, Shweta Singh, Yang Du, Vincenzo Coppola, Luke Stockwin, Nhu Nguyen, Lino Tessarollo, Leifur Thorsteinsson, Olafur E. Sigurjonsson, Sveinn Gudmundsson, Thorunn Rafnar, John F. Tisdale, Jonathan R. Keller. Cell Report; Volume 23, Issue 11, p3236–3248, 12 June 2018. https://doi.org/10.1016/j.celrep.2018.05.043
Santos S, Sigurjonsson OE, Custodio C, Mano JF. Tissue Eng Part B Rev. Blood plasma derivatives for tissue engineering and regenerative medicine therapies. 2018 May 8. https://doi.org/10.1089/ten.teb.2018.0008
Yurkovich JT, Bordbar A, Sigurjónsson ÓE, Palsson BO. Systems biology as an emerging paradigm in transfusion medicine. BMC Syst Biol. 2018 Mar 7;12(1):31. https://doi.org/10.1186/s12918-018-0558-x
Strunk, Dirk, Lozano, Miguel, Marks, Denese, Loh, Yen Siew, Gstraunthaler , Gerhard. Schennach, Harald, Rohde, Eva, Laner-Plamberger, Sandra, Nystedt , Johanna, Korhonen, Matti, Bieback, Karen, Schäfer, Richard, Bakchoul, Tamam, Waidmann, Marc, Lotfi, Ramin, Rojewski, Marcus, Schrezenmeier, Hubert;, Jonsdottir-Buch, Sandra, Montazeri, Helena, Sigurjónsson, Olafur, Introna, Martino, Capelli, Chiara, Falanga, Anna, Iudicone, Paola, Fioravanti, Daniela, Pierelli, Luca, Takanashi, Minoko, López-Villar, Olga, Burnouf, Thierry, Reems, Jo-Anna, Pierce, Jan, Preslar, Amber, Schallmoser, Katharina. International Forum on GMP-grade human platelet lysate for cell propagation. Vox Sang. Vox Sang. 2018 Jan;113(1):e1-e25. https://doi.org/10.1111/vox.12593
Strunk, Dirk, Lozano, Miguel, Marks, Denese, Loh, Yen Siew, Gstraunthaler , Gerhard. Schennach, Harald, Rohde, Eva, Laner-Plamberger, Sandra, Nystedt , Johanna, Korhonen, Matti, Bieback, Karen, Schäfer, Richard, Bakchoul, Tamam, Waidmann, Marc, Lotfi, Ramin, Rojewski, Marcus, Schrezenmeier, Hubert;, Jonsdottir-Buch, Sandra, Montazeri, Helena, Sigurjónsson, Olafur, Introna, Martino, Capelli, Chiara, Falanga, Anna, Iudicone, Paola, Fioravanti, Daniela, Pierelli, Luca, Takanashi, Minoko, López-Villar, Olga, Burnouf, Thierry, Reems, Jo-Anna, Pierce, Jan, Preslar, Amber, Schallmoser, Katharina. International Forum on GMP-grade human platelet lysate for cell propagation: Summary. Vox Sang. Vox Sang. 2018 Jan;113(1):80-87. https://doi.org/10.1111/vox.12594
Marta Mikaelsdottir, Brynjar Vidarsson, Gudmundur Runarsson, Una Bjarnadottir, Pall T. Onundarson Olafur E. Sigurjonsson, Anna M. Halldorsdottir. A comparison of platelet quality between platelets from healthy donors and hereditary hemochromatosis donors over seven‐day storage. Transfusion, First published: 09 November 2020. https://doi.org/10.1111/trf.16176
B Cells versus T Cells in the Tumor Microenvironment of Malignant Lymphomas. Are the Lymphocytes Playing the Roles of Muhammad Ali versus George Foreman in Zaire 1974? Minodora Desmirean , Sebastian Rauch, Ancuta Jurj, Sergiu Pasca, Sabina Iluta, Patric Teodorescu, Cristian Berce , Alina-Andreea Zimta, Adrian-Bogdan Tigu, Cristian Moldovan, Irene Paris, Jakob Steinheber, Cedric Richlitzki, Catalin Constantinescu, Olafur Eysteinn Sigurjonsson, Delia Dima, Bobe Petrushev and Ciprian Tomuleasa. J. Clin. Med. 2020, 9(11), 3412; https://doi.org/10.3390/jcm9113412
Overview of the Side-Effects of FDA- and/or EMA-Approved Targeted Therapies for the Treatment of Hematological Malignancies. Catalin Constantinescu, Sergiu Pasca, Alina-Andreea Zimta,Tiberiu Tat, Ioana Rus ,Patric Teodorescu,Sabina Iluta, Alina Tanase , Anca Colita , Olafur Sigurjonsson ,Hermann Einsele and Ciprian Tomuleasa. J. Clin. Med. 2020, 9(9), 2903; hhttps://doi.org/10.3390/jcm9092903
Rhesus D alloimmunization in pregnancy from 1996 to 2015 in Iceland: a nation-wide population study prior to routine antenatal anti-D prophylaxis.Gudlaugsson B, Hjartardottir H, Svansdottir G, Gudmundsdottir G, Kjartansson S, Jonsson T, Gudmundsson S, Halldorsdottir AM. Transfusion. 2020 Jan;60(1):175-183. https://doi.org/10.1111/trf.15635
The Malignant Role of Exosomes as Nanocarriers of Rare RNA Species. Alina-Andreea Zimta , Olafur Eysteinn Sigurjonsson, Diana Gulei and Ciprian Tomuleasa. J. Mol. Sci. 2020, 21(16), 5866. https://dx.doi.org/10.3390%2Fijms21165866
Human Embryonic-Derived Mesenchymal Progenitor Cells (hES-MP Cells) are Fully Supported in Culture with Human Platelet Lysates. Jonsdottir-Buch SM, Gunnarsdottir K, Sigurjonsson OE. Bioengineering (Basel). 2020 Jul 20;7(3):E75. https://doi.org/10.3390/bioengineering7030075
Continuous renal replacement therapy in cytokine release syndrome following immunotherapy or cellular therapies? . Constantinescu C, Pasca S, Tat T, Teodorescu P, Vlad C, Iluta S, Dima D, Tomescu D, Scarlatescu E, Tanase A, Sigurjonsson OE, Colita A, Einsele H, Tomuleasa C. J Immunother Cancer. 2020 May;8(1):e000742. https://doi.org/10.1136/jitc-2020-000742
Effects of amotosalen treatment on human platelet lysate bioactivity: A proof-of-concept study. Christensen C, Jonsdottir-Buch SM, Sigurjonsson OE. PLoS One. 2020 Apr 15;15(4):e0220163. https://dx.doi.org/10.1371%2Fjournal.pone.0220163
Current Status and Future Prospects of Genome-Scale Metabolic Modeling to Optimize the Use of Mesenchymal Stem Cells in Regenerative Medicine. Sigmarsdóttir Þ, McGarrity S, Rolfsson Ó, Yurkovich JT, Sigurjónsson ÓE. Front Bioeng Biotechnol. 2020; 8: 239. https://dx.doi.org/10.3389%2Ffbioe.2020.00239
Visualizing metabolic network dynamics through time-series metabolomic data. Buchweitz LF, Yurkovich JT, Blessing C, Kohler V, Schwarzkopf F, King ZA, Yang L, Jóhannsson F, Sigurjónsson ÓE, Rolfsson Ó, Heinrich J, Dräger A. BMC Bioinformatics. 2020 Apr 3;21(1):130. https://doi.org/10.1186/s12859-020-3415-z
Metabolomics study of platelet concentrates photochemically treated with amotosalen and UVA light for pathogen inactivation. Jóhannsson F, Árnason NÁ, Landrö R, Guðmundsson S, Sigurjonsson ÓE, Rolfsson Ó.Transfusion. 2020 Feb;60(2):367-377. https://doi.org/10.1111/trf.15610
Stefaniak, M, Gudjonsdottir M and Sigurjonsson OE. Fucoidan oligosaccharides-gold from the sea. Encyclopedia of Marine Biotechnology, Chapter 46. ISBN: 978-1-119-14377-2Wiley-Blackwell. https://doi.org/10.1002/9781119143802.ch46
Johannesdottir BK, Johannesdottir U, Jonsson T, Lund SH, Mogensen B, Gudbjartsson T. High Mortality from Major Vascular Trauma in Traffic Accidents: A Population-Based Study. Scand J Surg. 2020 Dec;109(4):328-335. https://doi.org/10.1177/1457496919863944
Dr. Níels Árni Árnason. Pathogen inactivation in platelet concentrate storage: Effects on quality and utilization. Reykjavik University. 2022
Dr. Adriana Milewska. Thesis: Development of SERS substrates for detecting differentiation in mesenchymal stromal cells. University of Iceland. 2021
Dr. Þóra Sigmarssdóttir: Modelling metabolomic changes in human Bone Marrow derived Mesenchymal Stem Cells during Osteogenic Differentiation via Genome scale metabolic models to further their use in Regenerative Medicine. Reykjavik University. 2021
Dr. Freyr Jóhannsson. Systems analysis of platelet metabolism during storage of platelet concentrates. Department of medicine University of Iceland. 2020
Dr. Magdalena Stefaniak. Bioactive properties of polysaccharides derived from Icelandic marine organisms. Department of food sciences University of Iceland. 2018
Dr. Joseph Lovecchio. University of Bologna/ Reykjavik University. Design and construction of a bioreactor system for bone formation. Department of Science and Engineering Reykjavik University. 2018.
Dr. Sandra Mjöll Jónsdóttir Buch. Osteogenesi and osteoimmunology of hES-MP derived osteoblasts: The potential of platelet lysates as serum substitute. Department of medicine University of Iceland. 2017
Dr. Björg Guðmundsdóttir. The function of POGZ1. Department of biology University of Iceland. 2014
Dr. Kristbjörn Orri Guðmundsson. Gene expression in hematopoietic stem cell development: Analysis of gene expression in different subpopulations of hematopoietic stem cells with relevance to self-renewal, commitment and differentiation. Department of medicine, University of Iceland. 2005.
Hekla Mjöll Finnbogadóttir. The impact of hereditary hemochromatosis on the expression of iron regulatory proteins in platelets. 2021
Joniada Dega. Forecasting future blood supply and demand in Iceland: a nationwide population-based study. Reykjavik University 2021
Gunnar Hákon Karlsson. The design and numerical analysis of a microfluidicssystem for osteogenic differentiation of mesenchymal stemcells. School of Engineering, Reykajvik University. 2021
Unnur Elísabet Stefánsdóttir. Bioactivity of Calanus finmarchicus as a side stream from the pelagic fish industry. Department of nutrition and food science, University of Iceland. 2021
Yousef Ingi Tamimi. Notkun neyðarblóðs á bráðamóttöku Landspítala. Ábendingar, afdrif og öyggi við inngjöf neyðarblóðs árin 2017 og 2018. Læknadeild, Háskóli Íslands. 2020
Zhaneta Shepeta. Effect of hemochromatosis on thrombin-induced platelet aggregation, platelet activation, and platelet metabolism. Quality of platelet units from hereditary hemochromatosis patients on maintenance phlebotomy. Department of medicine, University of Iceland. 2020
Davíð Snorrason M.Sc. escribing the glucose-lactate consumption rate during adipogenic differentiation of adult human bone marrow derived stem cells: A premise to explore possible model prediction of enzyme activity. School of Engineering, Reykjavik University. 2020
Christian Christensen M.Sc. he effects of amotosalen treatment on human platelet lysate bioactivity: Effects on proliferation and tri-lineage differentiation of mesenchymal stromal cells. Department of medicine, University of Iceland. 2019
Marta Mikaelsdóttir. Function of platelets in hemochromatosis patients. Department of medicine, University of Iceland. 2019
Sigurður Rúnar Rúnarsson M.Sc. Bioreactor system for osteogenic differentiation. School of Science and Engineering, Reykjavik University. 2019
Þóra Sigmarsdóttir. Describing the Glucose-Lactate Consumption Rate During Expansion and Osteogenic Differentiation of Human Bone Marrow Derived MSCs. School of science and engineering, Reykjavik University. 2018
Tim Diller. Using system dynamics and sustainable energy approaches to optimize blood stock management. Department of Technology Management and Economics, Chalmers University of Technology. 2018.
Sara Þöll Halldórsdóttir. Bioactivity of specialized platelet lysates without anticoagulants Department of medicine, University of Iceland. 2018.
Kristey Bríet Gísladóttir. Cytokine composition of platelet lysate derived from pathogen inactivated expired palteltes. Department of medicine, University of Iceland. 2018
Adriana Milewska. Magnesium infused biphasic calcium phosphate and chitosan grafted on glass as scaffolds for mesenchymal stem cells culture. Gdansk University of technology. 2016
Magda Ostrowska Magnesium infused biphasic calcium phosphate and chitosan grafted on glass as scaffolds for mesenchymal stem cells culture. Gdansk University of technology. 2016
Helena Montazeri. Project: Freeze dried platelet lysates from expired platelet concentrates support growth and differentiation of mesenchymal stem cells. Department of medicine, University of Iceland. 2016
Elísabet Edda Guðbjörnsdóttir. Developing a simulation model to better contril blood stock management. School of science and engineering, Reykjavík University. 2015.
Vigdís Jóhannsdóttir. Blood Donors in Iceland: A Nationwide Population-Based Study in 2005-2013. Department of medicince, University of Iceland. 2015.
Oddný Björgvinsdóttir. Investigating the effects of pulsed electromagnetic fields (PEMF) on bovine nucleus pulposus cells. School of science and engineering, Reykjavík University. 2014
Steinunn Guðmundsdóttir. Effect of chitin derivatives on macrophages: The role of chitinases and chitinase-like proteins. Department of medicine, University of Iceland. 2014
Kristbjörg Gunnarsdótir. The effect of expanding embryonic stem cell derived mesenchymal stem cells in media supplemented with lysate manufactured from fresh or expired platelet concentrates on chondrogenic differentiation. Department of medicine, University of Iceland). 2014.
Agnes Czenek. µCT and 3D modeling to monitor osteogenic differentiation on porus CaP scaffolds. School of science and engineering, Reykjavík University. 2014
Þröstur Pétursson. Risk analysis for patients undergoing total hip replacement. School of science and engineering, Reykjavík University. 2014
Benedikt Magnússon. Clinical Assessment and BMD analysis for patient Undergoing Total Hip Replacement. School of science and engineering, Reykjavík University. 2014
Guðlaug Jökulsdóttir. The Impact of demographics on future blood supply and demand in Iceland. . School of science and engineering, Reykjavík University. 2013
Ellen Óttarsdóttir. 3D modeling for clinical applications. School of science and engineering, Reykjavík University. 2013
Benjamín Sigurgeirsson. Sleep-Wake Modulation of Gene Expression in Zebrafish. School of science and engineering, Reykjavík University. 2013
Níels Árni Árnason M.Sc. The function of Dlg7 in embryonic hematopoiesis. Department of biology, University of Iceland. 2011
Helga Einarsdóttir. Blóðbankinn á Niðurskurðartímum. Háskólinn á Bifröst. 2010.
Ragnhildur Kolka Study on the pathogenesis of IgA nephropathy focusing on IgA1 glycosylation and the lectin pathway of the complement system. Læknadeild Háskóla Íslands. 2010
Helga Einarsdóttir. Arfgengar orsakir einstofna mótefnahækkunar og skyldra B-frumusjúkdóma. Department of medicine University of Iceland. 2009
Ramona Lieder. Chitinase-like-Proteins in Mesenchymal Stromal Cells and Bone Development. Ramona Lieder. F/H Campus Wien. 2009.
Örn Þ. Þorvarðarson. Fjárveitingar til Heilbrigðis- og menntamála árin 2000 til 2008. Samanburður á fjárvetingum til Landspítala og Háskóla Íslands. Viðskiptadeild Háskólans á Bifröst. 2009
Martin Speth M.Sc. Functional neuronal differentiation of genetically modified mouse neural stem cells in a regenerating chicken embryo spinal cord. Department of Medicine, University of Oslo. 2007
Marín Þórsdóttir. Ég get og geri. Hversvegna gefur fólk blóð? Háskóli Íslands, Félagsvísindadeild. 2002
Kristín Erla Harðardóttir. Þeim rennur blóðið til skyldunnar: Blóðgjafir Íslendinga í mannfræðilegu ljósi. Háskóli Íslands, Félagsvísindadeild. 2002
Ólafur E. Sigurjónsson. Megakaryocyte development in vitro: Differentiation, ploidy and apoptosis. Department of medicine, University of Iceland. Leiðbeinendur: Sveinn Guðmundsson, Vilhelmína Haraldsdóttir. 2001.
Kristbjörn Orri Guðmundsson. CD34+ frumur og B-eitilfrumur í naflastrengsblóði: blóðmyndandi forverafrumur, þroskaferill B-frumna og mótefnamyndandi B-frumur. Department of medicine, University of Iceland. 1998.
sem lífmerki fyrir járnhag hjá blóðgjöfum. Læknadeild, Háskóli Íslands. 2017
Kathrin Plawecki. Cytokine Secretion by PBMCs following a Co-Culture with Human Mesenchymal Stromal Cells treated with Platelet-Based Culture Supplements. Fachhochschule FH Campus Wien. 2016
Bjarnveig Ólafsdóttir. Sameindaerfðafræðileg skimun á RhD blóðflokki fósturs: Aðferðaþróun. Læknadeild, Háskóli Íslands. 2016
Camilla Klavik. Effect of pathogen inactivation on platelet secretomics in buffy coat - derived platelet concentrates during storage. Quantitation of sCD40L, sCD62P/sP-Selectin, CCL5/RANTES, CXCL4/PF4 and Glycocalicin/CD42b using ELISA. Department of medicine, University of Iceland. 2015
Snædís Vala Kristleifsdóttir. The effect of red blood cell storage on in vitro erythrophagocytosis. Department of medicine, University of Iceland. 2015
Sandra Dögg Vatnsdal. Tjáning á CD40 og CD40L á B- og T-eitilfrumum fyrir og eftir örvun. Samanburður á örvunaraðferðum. Læknadeild, Háskóli Íslands. 2014
Kristbjörg Gunnarsdóttir. The effect of expanding mesenchymal stem cells in media supplemented with lysate manufactured from fresh or expired platelet concentrates on chondrogenic differentiation. Department of medicine, University of Iceland. 2013
Sandra Mjöll Jónsdóttir Buch. The effect of expanding mesenchymal stem cells in media supplemented with lysate manufactured from fresh or expired platelet concentrates on chondrogenic differentiation. Department of medicine, University of Iceland.2012
Salóme Ingólfsdóttir. The effect of expanding mesenchymal stem cells in media supplemented with lysate manufactured from fresh or expired platelet concentrates on chondrogenic differentiation. Department of medicine, University of Iceland. 2012
Hulda Rós Gunnarsdóttir. Áhrif blóðflögulýsata, framleiddum úr útrunnum blóðflögueiningum á frumufjölgun og sérhæfingu Mesenchymal stofnfrumna. Department of biology, University of Iceland. 2010
Una Kristín Pétursdóttir. Tjáning á anti-örveru peptíðum í brjóskfrumum sem þroskast úr fósturbandvefs stofnfrumum (MSC – mesenchymal stem cells). Háskólinn í Reykjavík, Lífeindafræði 2008.
Rósa Halldóra Hansdóttir. Háskólinn í Reykjavík, Lífeindafræði 2008
Fernanda Rocha. The influence of platelets on specification and activity of T-regulatory cells and Th17 effector cells. Department of biology, University of Iceland. 2020.
Stefanía Davíðsdóttir. Blóð- og járnhagur kvenkyns blóðgjafa og tengsl við meðgöngu- og fæðingasög. Læknadeild, Háskóli Íslands. 2020.
Erla Gestsdóttir. Járnhagur íslenskra blóðgjafa í Blóðbankanum 1997 – 2018. Læknadeild, Háskóli Íslands. 2019
Thelma Kristinsdóttir. Erfðir og algengi járnskortsblóðleysis á Íslandi. Læknadeild, Háskóli Íslands. 2019
Jóhann Ragnarsson. Áhrif stökkbreytinga í HFE geninu á járnbúskap. Læknadeild, Háskóli Íslands. 2019
Brynjar Guðlaugsson. Rhesus D mótefni á meðgöngu árin 1996-2015. Læknadeild, Háskóli Íslands. 2018.
Alexander Sigurðsson. Háskammta krabbameinslyfjameðferð með eigin stofnfrumuígræðslu á Landspítala háskólasjúkrahúsi 2004-2017. Læknadeild, Háskóli Íslands. 2018.
Hrafn Hliðdal Þorvaldsson. Langvinnt eitilfrumuhvítblæði á Íslandi 2003-2016: Lifun, lyfja- og blóðhlutameðferð. Læknadeild, Háskóli Íslands. 2017.
Gunnar Bollason. Greining rauðkornamótefna kvenna á Íslandi árin 1996-2015. Áhrif á meðgöngu og afdrif nýbura. Læknadeild, Háskóli Íslands. 2016.
Kristján Torfi Örnólfsson. Þróun á aðferð til sérhæfingar miðlagsstofnfrumna. Mat á áhrifum frostþurrkunar á notagildi roflausna úr útrunnum örveruóvirkjuðum blóðflögueiningum við beinsérhæfingu miðlagsstofnfrumna. Læknadeild, Háskóli Íslands. 2015.
Gunnar Björn Ólafsson. Langvinnt eitilfrumuhvítblæði. Nýgengi, aðdragandi greiningar og undanfari. Læknadeild, Háskóli Íslands. 2014.
Davíð Ólafsson. Greining DNA skemmda í frystum og ófrystum stofnfrumueiningum og einkjarnafrumum úr heilblóðseiningum. Læknadeild, Háskóli Íslands. 2013
Þórdís Kristinsdóttir. Jákvætt Coombs próf hjá nýburum: Orsakir og afleiðingar. Læknadeild, Háskóli Íslands. 2013
Nedim Kasumacic Defining sub-population of hematopoietic stem/ progenitor cells that can differentiate to functional neurons of in a regenerating chicken embryo spinal cord. Department of Medicine, University of Oslo. 2007